Certain hormones unique to obese people can lead to an accumulation of fat in the liver. Compared with people who are not obese, cholesterol levels of obese people are higher, which hinders the solubility of bile. It is reported that 50-80% of women suffering from cholelithiasis are obese. Between obese women and those with normal weights, the former of the incidence of gallstones are about 6 times higher than the latter.